Failure of manganese to protect from Shiga toxin.

Shiga toxin (Stx), the main virulence factor of Shiga toxin producing Escherichia coli, is a major public health threat, causing hemorrhagic colitis and hemolytic uremic syndrome. Currently, there are no approved therapeutics for these infections; however manganese has been reported to provide prote...

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Bibliographic Details
Main Authors: Marsha A Gaston, Christine A Pellino, Alison A Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3713051?pdf=render