Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression
Abstract Background Recent studies have shown that the classic hypoglycemic drug metformin inhibits tumor growth; however, the underlying mechanism remains unclear. We previously showed that metformin disrupts the sponge effect of long non-coding RNA MALAT1/miR-142-3p to inhibit cervical cancer cell...
Main Authors: | Chenglai Xia, Chang Liu, Zhihong He, Yantao Cai, Jinman Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
|
Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-020-01627-6 |
Similar Items
-
iTRAQ-based quantitative proteomic analysis of the inhibition of cervical cancer cell invasion and migration by metformin
by: Chenglai Xia, et al.
Published: (2020-03-01) -
Downregulation of RAGE Inhibits Cell Proliferation and Induces Apoptosis via Regulation of PI3K/AKT Pathway in Cervical Squamous Cell Carcinoma
by: Li R, et al.
Published: (2020-03-01) -
SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway
by: Rong Hu, et al.
Published: (2018-11-01) -
Metformin Potentiates the Anticancer Effect of Everolimus on Cervical Cancer In Vitro and In Vivo
by: Ya-Hui Chen, et al.
Published: (2021-09-01) -
Metformin inhibits the proliferation of rheumatoid arthritis fibroblast-like synoviocytes through IGF-IR/PI3K/AKT/m-TOR pathway
by: Kun Chen, et al.
Published: (2019-07-01)