Synthesis of new alkyl derivatives of N(1)-(2’-bromo-1’,1’-difluoro-2’-chloroethyl)uracil with potential antitumor activity
The most common ways of their chemical modification are used namely, electrophilic and nucleophilic substitution reactions during the purposeful search for active substances among pyrimidines with aromatic properties. Antimetabolites of pyrimidine metabolism are one of the objects of the most succes...
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2020-08-01
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| Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
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| Online Access: | http://pharmed.zsmu.edu.ua/article/view/207064/207460 |