Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes.

Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes.

BACKGROUND: Recognition of lipopolysaccharide (LPS) is required for effective defense against invading gram-negative bacteria. Recently, in vitro studies revealed that CD14 is required for activation of the myeloid differentiation factor (MyD)88-dependent Toll-like receptor (TLR)4 signaling pathway...

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Bibliographic Details
Main Authors: Adam A Anas, Joppe W R Hovius, Cornelis van 't Veer, Tom van der Poll, Alex F de Vos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2855719?pdf=render

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