Factors Affecting the Power of Haplotype Markers in Association Studies

An important, unresolved question in genome-wide association studies is whether there are predictable differences in power between single nucleotide polymorphism (SNP) and haplotype markers. In this study, we use coalescent simulations to compare power for single-SNP and haplotype markers under a nu...

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Bibliographic Details
Main Authors: Martha T. Hamblin, Jean-Luc Jannink
Format: Article
Language:English
Published: Wiley 2011-07-01
Series:The Plant Genome
Online Access:https://dl.sciencesocieties.org/publications/tpg/articles/4/2/145