IDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact

IDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact

IDH1/2 mutation is the most frequent genomic alteration found in gliomas, affecting 40% of these tumors and is one of the earliest alterations occurring in gliomagenesis. We investigated a series of 1305 gliomas and showed that IDH mutation is almost constant in 1p19q codeleted tumors. We found that...

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Bibliographic Details
Main Authors: Xiao-Wei Wang, Pietro Ciccarino, Marta Rossetto, Blandine Boisselier, Yannick Marie, Virginie Desestret, Vincent Gleize, Karima Mokhtari, Marc Sanson, Marianne Labussière
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/540236

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http://dx.doi.org/10.1155/2014/540236

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