Dynamic changes of angiopoietins and endothelial nitric oxide supply during fluid resuscitation for major gyn-oncological surgery: a prospective observation

Dynamic changes of angiopoietins and endothelial nitric oxide supply during fluid resuscitation for major gyn-oncological surgery: a prospective observation

Abstract Background Despite goal-directed hemodynamic therapy, vascular function may deteriorate during surgery for advanced abdominal tumor masses. Fluid administration has been shown to be associated with distinct changes in serum levels of functional proteins. We sought to determine how serum tot...

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Bibliographic Details
Main Authors: Jennifer Gehlen, Sven Klaschik, Claudia Neumann, Mignon-Denise Keyver-Paik, Alexander Mustea, Martin Soehle, Stilla Frede, Markus Velten, Andreas Hoeft, Tobias Hilbert
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Translational Medicine
Subjects:
Angiopoietins
Nitric oxide
eNOS
Microvascular reactivity
Fluid resuscitation
Online Access:https://doi.org/10.1186/s12967-020-02236-9

Internet

https://doi.org/10.1186/s12967-020-02236-9

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