Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation

Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation

Mayaro virus (MAYV) is an emerging arthritogenic alphavirus belonging to the Togaviridae family. Infection leads to a dengue-like illness accompanied by severe polyarthralgia. However, the molecular and cellular mechanisms of arthritis as a result of MAYV infection remain poorly understood. In the p...

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Bibliographic Details
Main Authors: Michèle Bengue, Pauline Ferraris, Cécile Baronti, Cheikh Tidiane Diagne, Loïc Talignani, Sineewanlaya Wichit, Florian Liegeois, Catherine Bisbal, Antoine Nougairède, Dorothée Missé
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Viruses
Subjects:
arbovirus
Mayaro virus
matrix metalloproteinases
extracellular matrix
chondrocyte
synoviocyte
osteoblast
innate immunity
IL-6
TNF-α
Online Access:https://www.mdpi.com/1999-4915/11/9/797

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https://www.mdpi.com/1999-4915/11/9/797

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