Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants.

Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants.

OBJECTIVE:Reliable detection of HIV minority resistant variants (MRVs) requires bioinformatics analysis with specific algorithms to obtain good quality alignments. The aim of this study was to analyze ultra-deep sequencing (UDS) data using different analysis pipelines. METHODS:HIV-1 protease, revers...

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Main Authors: Marine Perrier, Nathalie Désiré, Alexandre Storto, Eve Todesco, Christophe Rodriguez, Mélanie Bertine, Quentin Le Hingrat, Benoit Visseaux, Vincent Calvez, Diane Descamps, Anne-Geneviève Marcelin, Charlotte Charpentier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983569?pdf=render

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http://europepmc.org/articles/PMC5983569?pdf=render

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