Arsenite-induced stress signaling: Modulation of the phosphoinositide 3′-kinase/Akt/FoxO signaling cascade

FoxO transcription factors and their regulators in the phosphoinositide 3′-kinase (PI3K)/Akt signaling pathway play an important role in the control of cellular processes involved in carcinogenesis, such as proliferation and apoptosis. We have previously demonstrated that physiologically relevant h...

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Bibliographic Details
Main Authors: Ingrit Hamann, Lars-Oliver Klotz
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231712000158