Camptothecin and khat (<it>Catha edulis </it>Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIP<sub>L</sub>, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
<p>Abstract</p> <p>Background</p> <p>An organic extract of the recreational herb khat (<it>Catha edulis </it>Forsk.) triggers cell death in various leukemia cell lines <it>in vitro</it>. The chemotherapeutics camptothecin, a plant alkaloid topois...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-11-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/8/1/101 |