Camptothecin and khat (<it>Catha edulis </it>Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIP<sub>L</sub>, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines

<p>Abstract</p> <p>Background</p> <p>An organic extract of the recreational herb khat (<it>Catha edulis </it>Forsk.) triggers cell death in various leukemia cell lines <it>in vitro</it>. The chemotherapeutics camptothecin, a plant alkaloid topois...

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Main Authors: Fossan Kjell O, Skavland Jørn, Wergeland Line, Hagland Hanne R, Dimba Elizabeth AO, Bredholt Therese, Tronstad Karl J, Johannessen Anne C, Vintermyr Olav K, Gjertsen Bjørn T
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/101