EF24 induces ferroptosis in osteosarcoma cells through HMOX1

EF24 induces ferroptosis in osteosarcoma cells through HMOX1

Purpose: EF24, a synthetic analogue of curcumin, was developed as an anti-tumor compound to induce apoptosis, inhibit proliferation and metastasis in various cancers. However, whether EF24 induces ferroptosis in osteosarcoma cells or not, and its underlying mechanism remains largely elusive. Methods...

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Bibliographic Details
Main Authors: Haiyingjie Lin, Xiaoting Chen, Chengyong Zhang, Tingting Yang, Zhendong Deng, Yuwei Song, Lanlan Huang, Fuxiang Li, Qingchu Li, Shaoqiang Lin, Dadi Jin
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
EF24
HMOX1
Ferroptosis
Osteosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313950

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http://www.sciencedirect.com/science/article/pii/S0753332220313950

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