Irradiated Human Dermal Fibroblasts Are as Efficient as Mouse Fibroblasts as a Feeder Layer to Improve Human Epidermal Cell Culture Lifespan

Irradiated Human Dermal Fibroblasts Are as Efficient as Mouse Fibroblasts as a Feeder Layer to Improve Human Epidermal Cell Culture Lifespan

A fibroblast feeder layer is currently the best option for large scale expansion of autologous skin keratinocytes that are to be used for the treatment of severely burned patients. In a clinical context, using a human rather than a mouse feeder layer is desirable to reduce the risk of introducing an...

Full description

Bibliographic Details
Main Authors: Lucie Germain, Sylvain L. Guérin, François A. Auger, Odile Damour, Carolyne Simard-Bisson, Éloise Rochefort, Karine Zaniolo, Danielle Larouche, Amélie Lavoie, Francis Bisson
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
feeder layer
i3T3
Sp1
human
skin
keratinocyte
differentiation
proliferation
microarray
gene profiling
Online Access:http://www.mdpi.com/1422-0067/14/3/4684

Internet

http://www.mdpi.com/1422-0067/14/3/4684

Similar Items