The regulation of immune responses by DC derived Type I IFN

Our immune system bears the tremendous task of mounting effective anti-microbial responses whilst maintaining immunoregulatory functions to avoid autoimmunity. In order to quickly respond to pathogens, Dendritic cells (DC) are armed with pattern recognition receptors (PRRs), allowing them to recogni...

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Bibliographic Details
Main Authors: Jennifer eGommerman, Dennis eNg
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00094/full