Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells

Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells

Abstract Background Lipotoxicity plays an important role in the pathogenesis of kidney injury. Our previous study demonstrated that activation of local renin-angiotensin system (RAS) was involved in saturated free fatty acids palmitic acid (PA)-induced tubular cell injuries. The current study aims t...

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Bibliographic Details
Main Authors: Miaojuan Qiu, Suchun Li, Lizi Jin, Pinning Feng, Yonglun Kong, Xiaoduo Zhao, Yu Lin, Yunyun Xu, Chunling Li, Weidong Wang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Lipids in Health and Disease
Subjects:
Chymostatin
ER stress
Lipid
Kidney
Online Access:http://link.springer.com/article/10.1186/s12944-018-0818-1

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http://link.springer.com/article/10.1186/s12944-018-0818-1

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