Not so unique to Primates: The independent adaptive evolution of TRIM5 in Lagomorpha lineage.

The plethora of restriction factors with the ability to inhibit the replication of retroviruses have been widely studied and genetic hallmarks of evolutionary selective pressures in Primates have been well documented. One example is the tripartite motif-containing protein 5 alpha (TRIM5α), a cytopla...

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Bibliographic Details
Main Authors: Ana Águeda-Pinto, Ana Lemos de Matos, Ana Pinheiro, Fabiana Neves, Patrícia de Sousa-Pereira, Pedro J Esteves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226202