Novel combination of CRISPR-based gene drives eliminates resistance and localises spread

Abstract Invasive species are among the major driving forces behind biodiversity loss. Gene drive technology may offer a humane, efficient and cost-effective method of control. For safe and effective deployment it is vital that a gene drive is both self-limiting and can overcome evolutionary resista...

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Bibliographic Details
Main Authors: Nicky R. Faber, Gus R. McFarlane, R. Chris Gaynor, Ivan Pocrnic, C. Bruce A. Whitelaw, Gregor Gorjanc
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83239-4