Synthetic Fragments of Receptor for Advanced Glycation End Products Bind Beta-Amyloid 1–40 and Protect Primary Brain Cells From Beta-Amyloid Toxicity
Receptor for advanced glycation end products (RAGE) is involved in the pathogenesis of Alzheimer’s disease. We have previously revealed that RAGE fragment sequence (60–76) and its shortened analogs sequence (60–70) and (60–65) under intranasal insertion were able to restore memory and improve morpho...
Main Authors: | Anna V. Kamynina, Noemi Esteras, Dmitriy O. Koroev, Natalia V. Bobkova, Samson M. Balasanyants, Ruben A. Simonyan, Armine V. Avetisyan, Andrey Y. Abramov, Olga M. Volpina |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-09-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2018.00681/full |
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