Tumour cell–derived extracellular vesicles interact with mesenchymal stem cells to modulate the microenvironment and enhance cholangiocarcinoma growth

The contributions of mesenchymal stem cells (MSCs) to tumour growth and stroma formation are poorly understood. Tumour cells can transfer genetic information and modulate cell signalling in other cells through the release of extracellular vesicles (EVs). We examined the contribution of EV-mediated i...

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Bibliographic Details
Main Authors: Hiroaki Haga, Irene K. Yan, Kenji Takahashi, Joseph Wood, Abba Zubair, Tushar Patel
Format: Article
Language:English
Published: Taylor & Francis Group 2015-01-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/view/24900/pdf_4