Asymmetry of chromosome Replichores renders the DNA translocase activity of FtsK essential for cell division and cell shape maintenance in Escherichia coli.

Bacterial chromosomes are organised as two replichores of opposite polarity that coincide with the replication arms from the ori to the ter region. Here, we investigated the effects of asymmetry in replichore organisation in Escherichia coli. We show that large chromosome inversions from the termina...

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Bibliographic Details
Main Authors: Christian Lesterlin, Carine Pages, Nelly Dubarry, Santanu Dasgupta, François Cornet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2585057?pdf=render