Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene.

Genetic and epigenetic alterations observed at end stage OSCC formation could be considered as a consequence of cancer development and thus changes in normal or premalignant tissues which had been exposed to oral carcinogens such as Dibenzo[def,p]chrysene (DBP) may better serve as predictive biomark...

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Bibliographic Details
Main Authors: Yuan-Wan Sun, Kun-Ming Chen, Yuka Imamura Kawasawa, Anna C Salzberg, Timothy K Cooper, Carla Caruso, Cesar Aliaga, Junjia Zhu, Krishne Gowda, Shantu Amin, Karam El-Bayoumy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5658092?pdf=render