MiRNA-mediated control of HLA-G expression and function.

MiRNA-mediated control of HLA-G expression and function.

HLA-G is a non-classical HLA class-Ib molecule expressed mainly by the extravillous cytotrophoblasts (EVT) of the placenta. The expression of HLA-G on these fetal cells protects the EVT cells from immune rejection and is therefore important for a healthy pregnancy. The mechanisms controlling HLA-G e...

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Bibliographic Details
Main Authors: Irit Manaster, Debra Goldman-Wohl, Caryn Greenfield, Daphna Nachmani, Pinchas Tsukerman, Yaron Hamani, Simcha Yagel, Ofer Mandelboim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3306401?pdf=render

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http://europepmc.org/articles/PMC3306401?pdf=render

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