Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating Nuclear factor - like 2 and Sirtuin 2 signaling pathways

The anti-tumor and anti-inflammatory effects of limonin have been established, here, we aim to explore whether limonin can induce protective effects against doxorubicin (DOX)-mediated cardiotoxicity which limits its clinical application. We found that limonin attenuated DOX-mediated cytoxicology of...

Full description

Bibliographic Details
Main Authors: Jie Deng, Min Huang, Hao Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Bioengineered
Subjects:
Online Access:http://dx.doi.org/10.1080/21655979.2021.1985299