Calibration and functional analysis of three genetically encoded Cl−/pH sensors

Calibration and functional analysis of three genetically encoded Cl−/pH sensors

Monitoring of the intracellular concentrations of Cl− and H+ requires sensitive probes that allow reliable quantitative measurements without perturbation of cell functioning. For these purposes the most promising are genetically encoded fluorescent biosensors, which have become powerful tools for no...

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Bibliographic Details
Main Authors: Marat eMukhtarov, Lavinia eLiguori, Tanya eWaseem, Francesco eRocca, Svetlana eBuldakova, Daniele eArosio, Piotr eBregestovski
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
intracellular pH
optogenetics
fluorescent bioSensors
intracellular chloride
non-invasive monitoring
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00009/full

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