A facile microwave assisted one pot synthesis of novel xanthene derivatives as potential anti-inflammatory and analgesic agents

A facile microwave assisted one pot synthesis of novel xanthene derivatives as potential anti-inflammatory and analgesic agents

Microwave assisted irradiation of resorcinol and substituted aryl aldehydes using sulfamic acid as catalyst afforded novel 9-aryl-9H-xanthene-3,6-diol derivatives (1a–f) in good yields. The newly synthesized compounds which were previously selected on the basis of PASS prediction were tested for ant...

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Bibliographic Details
Main Authors: Anupam G. Banerjee, Lata P. Kothapalli, Piyoosh A. Sharma, Asha B. Thomas, Rabindra K. Nanda, Sushant K. Shrivastava, Vivek V. Khatanglekar
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Arabian Journal of Chemistry
Subjects:
Xanthene
Microwave reaction
Sulfamic acid
Anti-inflammatory activity
Analgesic activity
PASS prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535211001535

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http://www.sciencedirect.com/science/article/pii/S1878535211001535

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