Solubility and dissolution enhancement of flurbiprofen by solid dispersion using hydrophilic carriers

Solubility and dissolution enhancement of flurbiprofen by solid dispersion using hydrophilic carriers

ABSTRACT The intent of the current work is to study the effect of polyethylene glycol 8000 and polyethylene glycol 10000 as hydrophilic carriers on dissolution behaviour of flurbiprofen. In the present study, solvent evaporation method was used to prepare flurbiprofen solid dispersions and evaluated...

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Bibliographic Details
Main Authors: Bhaskar Daravath, Chella Naveen, Sateesh Kumar Vemula, Rama Rao Tadikonda
Format: Article
Language:English
Published: Universidade de São Paulo 2018-05-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Polyethylene glycol/effects
Flurbiprofen/solubility
Flurbiprofen/dissolution rate
Drug-carrier compatibility/study
Dissolution efficiency
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400625&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400625&lng=en&tlng=en

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