miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

Abstract Programmed cell death 4 (PDCD4) is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer (CRC). During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecular mechanism for decreased PDCD4 expression is not...

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Bibliographic Details
Main Authors: Yanqing Liu, Uzair-ur-Rehman, Yu Guo, Hongwei Liang, Rongjie Cheng, Fei Yang, Yeting Hong, Chihao Zhao, Minghui Liu, Mengchao Yu, Xinyan Zhou, Kai Yin, Jiangning Chen, Junfeng Zhang, Chen-Yu Zhang, Feng Zhi, Xi Chen
Format: Article
Language:English
Published: SpringerOpen 2016-09-01
Series:Protein & Cell
Subjects:
microRNA
colorectal cancer
miR-181b
PDCD4
Online Access:http://link.springer.com/article/10.1007/s13238-016-0313-2

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http://link.springer.com/article/10.1007/s13238-016-0313-2

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