Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

<h4>Background</h4>Anthelminthic treatment options against schistosomiasis are limited. The current treatment relies almost exclusively on a single drug, praziquantel (PZQ). As a consequence, the development of resistance to PZQ and limited activity of PZQ against earlier development sta...

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Bibliographic Details
Main Authors: Nermina Vejzagić, Ulrich Fabien Prodjinotho, Nagwa El-Khafif, Ruili Huang, Anton Simeonov, Thomas Spangenberg, Clarissa Prazeres da Costa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009432

Internet

https://doi.org/10.1371/journal.pntd.0009432

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