Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance

<p>Abstract</p> <p>Background</p> <p>Anthracyclines and taxanes are commonly used in the treatment of breast cancer. However, tumor resistance to these drugs often develops, possibly due to overexpression of drug transporters. It remains unclear whether drug resistance...

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Bibliographic Details
Main Authors: Veitch Zachary, Guo Baoqing, Villeneuve David J, Laberge Monique L, Hembruff Stacey L, Cecchetto Melanie, Parissenti Amadeo M
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/318