A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study

A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study

A large number of clinical studies have shown that interleukin-18 (IL-18) plasma levels are positively correlated with the pathogenesis and development of type 2 diabetes mellitus (T2DM), but it remains unclear whether IL-18 causes T2DM, primarily due to the influence of reverse causality and residu...

Full description

Bibliographic Details
Main Authors: He Zhuang, Junwei Han, Liang Cheng, Shu-Lin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
interleukin-18 levels
type 2 diabetes mellitus
casual effect
Mendelian randomization
genome-wide association studies
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00295/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00295/full

Similar Items