A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains

A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains

Background/Aims: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH). This study sought to cross these USH-like mice (named KMush...

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Bibliographic Details
Main Authors: Weiming Yan, Pan Long, Tao Chen, Wei Liu, Lu Yao, Ze Ren, Xiangqian Li, Jiancong Wang, Junhui Xue, Ye Tao, Lei Zhang, Zuoming Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Retinitis pigmentosa
Usher syndrome
Electroretinogram
Auditory brainstem response
Inbred strain
Mutation
Online Access:https://www.karger.com/Article/FullText/491068

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https://www.karger.com/Article/FullText/491068

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