Sculpting humoral immunity through dengue vaccination to enhance protective immunity

Dengue viruses (DENV) are the most important mosquito transmitted viral pathogens infecting humans. DENV infection produces a spectrum of disease, most commonly causing a self-limiting flu-like illness known as dengue fever; yet with increased frequency, manifesting as life-threatening dengue hemorr...

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Bibliographic Details
Main Authors: Wayne eCrill, Holly R Hughes, Nicole B Trainor, Brent S Davis, Matt T Whitney, Gwong-Jen J Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00334/full