Carrying-over effects of GVBD blocking on post-blocking meiotic progression of oocytes: species difference and the signaling pathway leading to MPF activation.

Efforts to improve the quality of in vitro matured oocytes by blocking germinal vesicle breakdown (GVBD) and allowing more time for ooplasmic maturation have achieved little due to a lack of knowledge on the molecular events during GVBD blocking. Such knowledge is also important for studies aimed at...

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Bibliographic Details
Main Authors: Guang-Zhong Jiao, Hua-Yu Lian, Yan Gao, Ming-Ju Sun, Shuai Gong, Liang-Liang Zheng, Chuan-Xin Zhang, Jing-He Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4117542?pdf=render