Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children

Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children

Abstract Background The FcγRs genotypes have been reported to play a key role in the defence against malaria parasites through both cellular and humoral immunity. This study aimed to investigate the possible correlation between FcγR (IIa, IIIa, and IIIb) genes polymorphism and the clinical outcome f...

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Bibliographic Details
Main Authors: Amre Nasr, Ahmad Aljada, Osama Hamid, Hatim A. Elsheikh, Emad Masuadi, Ahmad Al-Bawab, Themer H. Alenazi, Amir Abushouk, Ayman M. Salah
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Malaria Journal
Subjects:
Plasmodium
Falciparum
Malaria
IgG subclass
AMA-1
Saudi
Online Access:https://doi.org/10.1186/s12936-021-03901-0

Internet

https://doi.org/10.1186/s12936-021-03901-0

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