Bayesian estimates of linkage disequilibrium
<p>Abstract</p> <p>Background</p> <p>The maximum likelihood estimator of <it>D' </it>– a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes.</p> &...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-06-01
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| Series: | BMC Genetics |
| Online Access: | http://www.biomedcentral.com/1471-2156/8/36 |