Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kappaB activation.

Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kappaB activation.

Carrageenan (CGN) is a high molecular weight sulphated polysaccharide derived from red seaweeds. In rodents, its degraded forms (dCGN) can induce intestinal inflammation associated with macrophage recruitment and activation. The aim of this study was: 1) to analyze the size-dependent effects of dCGN...

Full description

Bibliographic Details
Main Authors: Claudine Benard, Antonietta Cultrone, Catherine Michel, Carlos Rosales, Jean-Pierre Segain, Marc Lahaye, Jean-Paul Galmiche, Christine Cherbut, Hervé M Blottière
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20072622/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20072622/?tool=EBI

Similar Items