How Does Reprogramming to Pluripotency Affect Genomic Imprinting?

Human induced Pluripotent Stem Cells (hiPSCs) have the capacity to generate a wide range of somatic cells, thus representing an ideal tool for regenerative medicine. Patient-derived hiPSCs are also used for in vitro disease modeling and drug screenings. Several studies focused on the identification...

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Bibliographic Details
Main Authors: Valentina Perrera, Graziano Martello
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IPS
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00076/full