Safety and efficacy of umbilical cord-derived Wharton’s jelly compared to hyaluronic acid and saline for knee osteoarthritis: study protocol for a randomized, controlled, single-blind, multi-center trial

Abstract Background Osteoarthritis (OA) is the most common joint disorder in the United States of America (USA) with a fast-rising prevalence. Current treatment modalities are limited, and total knee replacement surgeries have shown disadvantages, especially for grade II/III OA. The interest in the...

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Bibliographic Details
Main Authors: Ashim Gupta, Nicola Maffulli, Hugo C. Rodriguez, Eric W. Carson, Randa A. Bascharon, Kristin Delfino, Howard J. Levy, Saadiq F. El-Amin
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02475-6