NGL-1/LRRC4C Deletion Moderately Suppresses Hippocampal Excitatory Synapse Development and Function in an Input-Independent Manner

NGL-1/LRRC4C Deletion Moderately Suppresses Hippocampal Excitatory Synapse Development and Function in an Input-Independent Manner

Netrin-G ligand-1 (NGL-1), also known as LRRC4C, is a postsynaptic densities (PSDs)-95-interacting postsynaptic adhesion molecule that interacts trans-synaptically with presynaptic netrin-G1. NGL-1 and its family member protein NGL-2 are thought to promote excitatory synapse development through larg...

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Bibliographic Details
Main Authors: Yeonsoo Choi, Haram Park, Hwajin Jung, Hanseul Kweon, Seoyeong Kim, Soo Yeon Lee, Hyemin Han, Yisul Cho, Seyeon Kim, Woong Seob Sim, Jeongmin Kim, Yongchul Bae, Eunjoon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
synapse
trans-synaptic adhesion
NGL-1
LRRC4C
PSD-95
synaptic transmission
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00119/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00119/full

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