BM-MSC Transplantation Alleviates Intracerebral Hemorrhage-Induced Brain Injury, Promotes Astrocytes Vimentin Expression, and Enhances Astrocytes Antioxidation via the Cx43/Nrf2/HO-1 Axis

BM-MSC Transplantation Alleviates Intracerebral Hemorrhage-Induced Brain Injury, Promotes Astrocytes Vimentin Expression, and Enhances Astrocytes Antioxidation via the Cx43/Nrf2/HO-1 Axis

Intracerebral hemorrhage (ICH) is a particularly severe form of stroke, and reactive astrogliosis is a common response following injury to the central nervous system (CNS). Mesenchymal stem cells (MSCs) are reported to promote neurogenesis and alleviate the late side effects in injured brain regions...

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Bibliographic Details
Main Authors: Xiao Chen, Huaibin Liang, Zhiyu Xi, Yong Yang, Huimin Shan, Baofeng Wang, Zhihong Zhong, Canxin Xu, Guo-Yuan Yang, Qingfang Sun, Yuhao Sun, Liuguan Bian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ICH
MSC
astrocytes
Cx43
Nrf2
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00302/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00302/full

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