Precise A•T to G•C base editing in the zebrafish genome

Abstract Background Base editors are a class of genome editing tools with the ability to efficiently induce point mutations in genomic DNA, without inducing double-strand breaks or relying on homology-direct repair as in other such technologies. Recently, adenine base editors (ABEs) have been develo...

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Bibliographic Details
Main Authors: Wei Qin, Xiaochan Lu, Yunxing Liu, Haipeng Bai, Song Li, Shuo Lin
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-018-0609-1