RNase A Treatment Interferes With Leukocyte Recruitment, Neutrophil Extracellular Trap Formation, and Angiogenesis in Ischemic Muscle Tissue

RNase A Treatment Interferes With Leukocyte Recruitment, Neutrophil Extracellular Trap Formation, and Angiogenesis in Ischemic Muscle Tissue

Background: RNase A (the bovine equivalent to human RNase 1) and RNase 5 (angiogenin) are two closely related ribonucleases. RNase 5 is described as a powerful angiogenic factor. Whether RNase A shares the same angiogenic characteristic, or interferes with vessel growth as demonstrated for arterioge...

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Bibliographic Details
Main Authors: Manuel Lasch, Konda Kumaraswami, Simona Nasiscionyte, Susanna Kircher, Dominic van den Heuvel, Sarah Meister, Hellen Ishikawa-Ankerhold, Elisabeth Deindl
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
angiogenesis
capillary sprouting
RNase A
RNase 5
extracellular RNA
leukocyte recruitment
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.576736/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.576736/full

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