High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance.

High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance.

BACKGROUND: Type 2 diabetes mellitus and muscle insulin resistance have been associated with reduced capacity of skeletal muscle mitochondria, possibly as a result of increased intake of dietary fat. Here, we examined the hypothesis that a prolonged high-fat diet consumption (HFD) increases the satu...

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Bibliographic Details
Main Authors: Joris Hoeks, Janneke de Wilde, Martijn F M Hulshof, Sjoerd A A van den Berg, Gert Schaart, Ko Willems van Dijk, Egbert Smit, Edwin C M Mariman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3225362?pdf=render

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http://europepmc.org/articles/PMC3225362?pdf=render

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