Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway

Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway

Oxidative stress contributes to muscle wasting in advanced chronic kidney disease (CKD) patients. Atractylenolide III (ATL-III), the major active constituent of Atractylodes rhizome, has been previously reported to function as an antioxidant. This study is aimed at investigating whether ATL-III has...

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Bibliographic Details
Main Authors: Mingqing Wang, Rong Hu, Yanjing Wang, Lingyu Liu, Haiyan You, Jiaxing Zhang, Xiaohui Wu, Tingting Pei, Fujing Wang, Lu Lu, Wei Xiao, Lianbo Wei
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1875471

Internet

http://dx.doi.org/10.1155/2019/1875471

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