In vitro recapitulation of functional microvessels for the study of endothelial shear response, nitric oxide and [Ca2+]i.

Microfluidic technologies enable in vitro studies to closely simulate in vivo microvessel environment with complexity. Such method overcomes certain constrains of the statically cultured endothelial monolayers and enables the cells grow under physiological range of shear flow with geometry similar t...

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Bibliographic Details
Main Authors: Xiang Li, Sulei Xu, Pingnian He, Yuxin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4429116?pdf=render