Sphere-Formation Assay: Three-Dimensional in vitro Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells

Cancer Stem Cells (CSCs) are a sub-population of cells, identified in most tumors, responsible for the initiation, recurrence, metastatic potential, and resistance of different malignancies. In prostate cancer (PCa), CSCs were identified and thought to be responsible for the generation of the lethal...

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Main Authors: Hisham F. Bahmad, Katia Cheaito, Reda M. Chalhoub, Ola Hadadeh, Alissar Monzer, Farah Ballout, Albert El-Hajj, Deborah Mukherji, Yen-Nien Liu, Georges Daoud, Wassim Abou-Kheir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00347/full