Collateral methotrexate resistance in cisplatin-selected murine leukemia cells
Resistance to anticancer drugs is a major cause of failure of many therapeutic protocols. A variety of mechanisms have been proposed to explain this phenomenon. The exact mechanism depends upon the drug of interest as well as the tumor type treated. While studying a cell line selected for its resist...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
1999-01-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700005 |