Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome

Osteoarthritis (OA) is characterized by a loss of extracellular matrix which is driven by catabolic cytokines. Proteomic analysis of the OA cartilage secretome enables the global study of secreted proteins. These are an important class of molecules with roles in numerous pathological mechanisms. Alt...

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Bibliographic Details
Main Authors: Mandy J. Peffers, Robert J. Beynon, Peter D. Clegg
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/10/20658