Eucannabinolide, a novel sesquiterpene lactone, suppresses the growth, metastasis and BCSCS-like traits of TNBC via inactivation of STAT3

Eucannabinolide, a novel sesquiterpene lactone, suppresses the growth, metastasis and BCSCS-like traits of TNBC via inactivation of STAT3

Signal transducer and activator of transcription 3 (STAT3) is an important therapeutic target to triple negative breast cancer (TNBC) treatment. In the present study, we aim to investigate the potential activity of Eucannabinolide (Euc), a novel sesquiterpene lactone separated from Eupatorium cannab...

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Bibliographic Details
Main Authors: Zhihui Zhu, Jingtao Yuan, Xintong Xu, Yingying Wei, Bo Yang, Huajun Zhao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Eucannabinolide
Triple negative breast cancer
STAT3
Proliferation
Metastasis
Breast cancer stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301676

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http://www.sciencedirect.com/science/article/pii/S1476558620301676

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