Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

<p>Abstract</p> <p>Background</p> <p>Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, resulting in fully che...

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Bibliographic Details
Main Authors: Chung Jae, Jeong Mikyoung, Montgomery John S, Balch Curt, Li Meng, Yan Pearlly, Huang Tim HM, Kim Sun, Nephew Kenneth P
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/2/34

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http://www.biomedcentral.com/1755-8794/2/34

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